As research becomes increasingly global, researchers must be mindful of federal regulations that govern the transfer of technologies, biological materials, software, and technical data. This session offers a comprehensive overview of export control laws including when these regulations apply and what constitutes an export, even within U.S. borders. Participants will also explore the broader domain of research security: how to responsibly manage international collaborations, safeguard sensitive data, and recognize emerging risk factors in open science. Case examples will be used to illustrate how these frameworks apply across disciplines.